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Chronic aspartame intake causes changes in the trans-sulphuration pathway, glutathione depletion and liver damage in mice

When antioxidants are not sufficient to deal with the effects of oxidants, oxidative stress can occur (Valko, Rhodes, Moncol, Izakovic, & Mazur, 2006)

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Moreover, intracellular staining for IL-5 and IL-13 ( Supplementary Figures 4HI ), corroborated with our previous findings that melatonin ILC2s produced less cytokine than vehicle treated controls ( Supplementary Figures 4BF, H, I )

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